WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:1903125 negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation GO

Namespace  biological_process Obsolete  false
Description  A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

25 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a protein. Includes protein modification.
GO:0036211 protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0006796 phosphate-containing compound metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GO:0006793 phosphorus metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus.
GO:0043412 macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GO:0016310 phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
GO:0006468 protein phosphorylation The process of introducing a phosphate group on to a protein.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0018193 peptidyl-amino acid modification The alteration of an amino acid residue in a peptide.
GO:0004601 peroxidase activity Catalysis of the reaction: a donor + a peroxide = an oxidized donor + 2 H2O.
GO:0016209 antioxidant activity Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
GO:0016684 oxidoreductase activity, acting on peroxide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.
GO:0140824 thioredoxin-dependent peroxiredoxin activity Catalysis of the reaction: [thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O.
GO:0008379 thioredoxin peroxidase activity Catalysis of the reaction: [thioredoxin]-dithiol + hydrogen peroxide = [thioredoxin]-disulfide + H2O.
GO:0051920 peroxiredoxin activity Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.
GO:0018107 peptidyl-threonine phosphorylation The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
GO:0018210 peptidyl-threonine modification The modification of peptidyl-threonine.
GO:1903125 negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity.

26 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0018107 GO:1903125
negatively regulates GO:0008379 GO:1903125
negatively regulates GO:0008379 GO:1903125
is_a GO:0018107 GO:1903125
is_a GO:0036211 GO:1903125
is_a GO:0008152 GO:1903125
negatively regulates GO:0016209 GO:1903125
is_a GO:0008150 GO:1903125
is_a GO:0016310 GO:1903125
is_a GO:0019538 GO:1903125
negatively regulates GO:0051920 GO:1903125
negatively regulates GO:0016684 GO:1903125
is_a GO:0018210 GO:1903125
is_a GO:0043170 GO:1903125
is_a GO:0018193 GO:1903125
negatively regulates GO:0003824 GO:1903125
negatively regulates GO:0016491 GO:1903125
is_a GO:0006468 GO:1903125
negatively regulates GO:0003674 GO:1903125
negatively regulates GO:0140824 GO:1903125
is_a GO:0044238 GO:1903125
negatively regulates GO:0004601 GO:1903125
is_a GO:0009987 GO:1903125
is_a GO:0006793 GO:1903125
is_a GO:0006796 GO:1903125
is_a GO:0043412 GO:1903125

3 Synonyms

Name Type
negative regulation of thiol peroxidase activity by peptidyl-threonine phosphorylation synonym
negative regulation of TPx activity by peptidyl-threonine phosphorylation synonym
negative regulation of TrxPx activity by peptidyl-threonine phosphorylation synonym