WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:1904602 serotonin-activated cation-selective channel complex GO

Namespace  cellular_component Obsolete  false
Description  A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

17 Parents

Identifier Name Description
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0071944 cell periphery The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.
GO:0098796 membrane protein complex Any protein complex that is part of a membrane.
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
GO:1990351 transporter complex A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.
GO:1902495 transmembrane transporter complex A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.
GO:0005886 plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0098797 plasma membrane protein complex Any protein complex that is part of the plasma membrane.
GO:0034703 cation channel complex An ion channel complex through which cations pass.
GO:0034702 monoatomic ion channel complex A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective monoatomic ion transport down its electrochemical gradient.
GO:0043235 receptor complex Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0098802 plasma membrane signaling receptor complex Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.
GO:0098878 neurotransmitter receptor complex Any protein complex that is capable of functioning as a neurotransmitter receptor.
GO:0098665 serotonin receptor complex A protein complex that is capable of serotonin receptor activity.
GO:1904602 serotonin-activated cation-selective channel complex A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist.

17 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0034703 GO:1904602
is_a GO:0098878 GO:1904602
is_a GO:0098665 GO:1904602
is_a GO:1902495 GO:1904602
part of GO:0016020 GO:1904602
part of GO:0071944 GO:1904602
is_a GO:0032991 GO:1904602
is_a GO:0098802 GO:1904602
is_a GO:0098796 GO:1904602
is_a GO:0098797 GO:1904602
is_a GO:1990351 GO:1904602
is_a GO:0034702 GO:1904602
is_a GO:0043235 GO:1904602
part of GO:0005575 GO:1904602
part of GO:0110165 GO:1904602
is_a GO:0005575 GO:1904602
part of GO:0005886 GO:1904602

5 Synonyms

Name Type
5-HT-3 receptor complex synonym
5-hydroxytryptamine receptor 3 complex synonym
5-HT3 receptor complex synonym
serotonin receptor complex synonym
5HT3 receptor complex synonym