WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:1990922 hepatic stellate cell proliferation GO

Namespace  biological_process Obsolete  false
Description  The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

5 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population.
GO:0048144 fibroblast proliferation The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.
GO:1990922 hepatic stellate cell proliferation The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver.

12 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
regulates GO:1990922 GO:1904897
regulates GO:1990922 GO:1904897
negatively regulates GO:1990922 GO:1904898
negatively regulates GO:1990922 GO:1904898
regulates GO:1990922 GO:1904898
positively regulates GO:1990922 GO:1904899
positively regulates GO:1990922 GO:1904899
regulates GO:1990922 GO:1904899
is_a GO:0048144 GO:1990922
is_a GO:0008150 GO:1990922
is_a GO:0008283 GO:1990922
is_a GO:0009987 GO:1990922

3 Synonyms

Name Type
hepatic perisinusoidal cell proliferation synonym
perisinusoidal cell proliferation synonym
Ito cell proliferation synonym