WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:1990936 vascular associated smooth muscle cell dedifferentiation GO

Namespace  biological_process Obsolete  false
Description  The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

10 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0032502 developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GO:0048869 cellular developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
GO:0036166 phenotypic switching A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.
GO:0043696 dedifferentiation The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors.
GO:0043697 cell dedifferentiation The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
GO:0090677 reversible differentiation A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another.
GO:0090678 cell dedifferentiation involved in phenotypic switching A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.
GO:1990936 vascular associated smooth muscle cell dedifferentiation The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.

19 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
regulates GO:1990936 GO:1905174
regulates GO:1990936 GO:1905174
negatively regulates GO:1990936 GO:1905175
negatively regulates GO:1990936 GO:1905175
regulates GO:1990936 GO:1905175
positively regulates GO:1990936 GO:1905176
positively regulates GO:1990936 GO:1905176
regulates GO:1990936 GO:1905176
is_a GO:0090678 GO:1990936
part of GO:0090677 GO:1990936
part of GO:0008150 GO:1990936
is_a GO:0008150 GO:1990936
is_a GO:0032502 GO:1990936
part of GO:0036166 GO:1990936
is_a GO:0048869 GO:1990936
is_a GO:0009987 GO:1990936
part of GO:0009987 GO:1990936
is_a GO:0043697 GO:1990936
is_a GO:0043696 GO:1990936

1 Synonyms

Name Type
vascular smooth muscle cell dedifferentiation synonym