WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:1990119 RNA helicase inhibitor activity GO

Namespace  molecular_function Obsolete  false
Description  Binds to and stops, prevents or reduces the activity of an RNA helicase.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

20 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify a nucleic acid.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0140657 ATP-dependent activity A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0140098 catalytic activity, acting on RNA Catalytic activity that acts to modify RNA.
GO:0016853 isomerase activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0120543 macromolecular conformation isomerase activity Catalysis of a reaction that alters the macromolecular conformation of a molecule.
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0060590 ATPase regulator activity Binds to and modulates the activity of an ATP hydrolysis activity.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0004857 enzyme inhibitor activity Binds to and stops, prevents or reduces the activity of an enzyme.
GO:0140678 molecular function inhibitor activity A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0004386 helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
GO:0120545 nucleic acid conformation isomerase activity Catalysis of a reaction that alters the conformation of a nucleic acid.
GO:0008186 ATP-dependent activity, acting on RNA Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.
GO:0003724 RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.
GO:0042030 ATPase inhibitor activity Binds to and stops, prevents or reduces an ATP hydrolysis activity.
GO:1990119 RNA helicase inhibitor activity Binds to and stops, prevents or reduces the activity of an RNA helicase.

24 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
negatively regulates GO:0003724 GO:1990119
is_a GO:0042030 GO:1990119
is_a GO:0004857 GO:1990119
regulates GO:0003824 GO:1990119
is_a GO:0098772 GO:1990119
is_a GO:0140678 GO:1990119
negatively regulates GO:0140657 GO:1990119
negatively regulates GO:0003824 GO:1990119
has part GO:0005515 GO:1990119
negatively regulates GO:0004386 GO:1990119
regulates GO:0003674 GO:1990119
is_a GO:0003674 GO:1990119
negatively regulates GO:0003674 GO:1990119
negatively regulates GO:0008186 GO:1990119
negatively regulates GO:0120543 GO:1990119
negatively regulates GO:0140098 GO:1990119
is_a GO:0060590 GO:1990119
negatively regulates GO:0120545 GO:1990119
regulates GO:0140657 GO:1990119
has part GO:0005488 GO:1990119
has part GO:0003674 GO:1990119
negatively regulates GO:0140640 GO:1990119
is_a GO:0030234 GO:1990119
negatively regulates GO:0016853 GO:1990119

1 Synonyms

Name Type
ATP-dependent RNA helicase inhibitor activity synonym