WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:1990455 PTEN phosphatase complex GO

Namespace  cellular_component Obsolete  false
Description  A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

6 Parents

Identifier Name Description
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:1903293 phosphatase complex A protein complex which is capable of phosphatase activity.
GO:1904144 phosphatidylinositol phosphate phosphatase complex A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity.
GO:1990455 PTEN phosphatase complex A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function.

5 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:1904144 GO:1990455
is_a GO:0032991 GO:1990455
is_a GO:0005575 GO:1990455
is_a GO:1903293 GO:1990455
is_a GO:1902494 GO:1990455

3 Synonyms

Name Type
phosphatase and tensin homolog deleted on chromosome ten homodimer synonym
phosphatase and tensin homolog synonym
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer synonym