WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr10003 Subcellular Localization  GFP:: COSA-1 is detected as a diffuse nucleoplasmic signal beginning in early pachytene and then displays a striking localization pattern later in pachytene that is consistent with expectations for a protein that marks crossover (CO) sites. Starting at the transition from mid to late pachytene and persisting through diplotene, GFP::COSA-1 localizes to 6.0 ± 0.2 bright foci per nucleus (n = 76), corresponding in number to the six COs - one per chromosome pair - that form during wild-type meiosis. At diplotene, GFP::COSA-1 localizes at the site of the single emerging chiasma on each homolog pair. We conclude that COSA-1 localizes to CO sites.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00022172 cosa-1 Y71H2AM.7 Caenorhabditis elegans

0 Life Stages