WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  pdhk-2p::GFP and PDHK-2::GFP are expressed mainly in the head neurons, pharynx, intestinal nuclei and intestine. PDHK-2::GFP was ubiquitously expressed in the dauer state. Primary Identifier  Expr10549
Subcellular Localization  PDHK-2::GFP was dispersed around the nuclei of intestinal cells in L4 worms under well-fed conditions but exhibited a punctate fluorescent pattern in the muscle of worms that had been maintained under 12-hour starvation conditions. These results suggest that localization of PDHK-2 is influenced by nutritional state.

3 Anatomy Terms

Definition Name Synonym Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages. intestine gut WBbt:0005772
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine. pharynx esophagus WBbt:0003681
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00022719 pdhk-2 ZK370.5 Caenorhabditis elegans

0 Life Stages