WormMine: ExpressionPattern Expr11951

• Primary Identifier: Expr11951
• Subcellular Localization: At a higher resolution, ZTF-8 signal is observed as foci both on chromosomes as well as in the nucleolus. Specifically, 34% of ZTF-8 foci at the premeiotic tip, and 78% at late pachytene, localize to DAPI-stained chromosomes, with the remaining foci being localized to the nucleolus. ZTF-8 localization is also observed in gut and embryonic nuclei. ZTF-8 localizes to both chromatin and the nucleolus. ZTF-8 signal is observed in mitotic nuclei at the gonadal distal tip (premeiotic tip). This signal is then reduced upon entrance into meiosis (leptotene/zygotene stages = transition zone) and remains weak through the mid-pachytene stage. However, the ZTF-8 signal increases once again in late pachytene nuclei and persists through late diakinesis oocytes. This dynamic pattern of expression suggests regulation of ZTF-8 during meiotic prophase.

3 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
organ producing either sperm or ova.	gonad		WBbt:0005175
cell that exists in and is part of an embryo.	embryonic cell		WBbt:0007028

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00022598	ztf-8	ZC395.8	Caenorhabditis elegans

0 Life Stages