WormMine: ExpressionPattern Expr687

• Pattern: Expression is observed in newly hatched L1 larvae and late stage embryos. There is strong staining of the marginal cells (AB-derived) in the pharynx; also there is staining in the posterior gut near the anal region (cells may be sphincter cells, rectal intestinal valve or the posterior intestinal muscle cells). L1-L4 pharyngeal cells and cells in the posterior gut region (staining of posterior cells reduces in later stages). L1-L2 occasional staining in the gut lumen or posterior intestinal cells. Intensity of staining in intestinal lumen decreases gradually during L2, L3 and L4 BUT pharyngeal cells continue to stain. Adults: rare intestinal staining and strong pharyngeal staining is observed klp-3 gene may be expressed in sphincter muscle of the intestino-rectal valve and the intestinal muscles located anterior to the anus which are attached to the intestine and body wall. The stained cells in posterior intestinal region are descendants of AB founder cells.
• Primary Identifier: Expr687
• Remark: Reporter gene fusion type not specified. This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope).

5 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a saddle-shaped muscle cell that encircles the intestinal-rectal valve	anal sphincter muscle	lineage name: ABprpppppap	WBbt:0005798
intestinal muscle cell, attach to intestine and body wall anterior to anus	intestinal muscle	stomato-intestinal muscle	WBbt:0005796
Intestino-rectal valve	virL	lineage name: ABprpappppp	WBbt:0004511
Intestino-rectal valve	virR	lineage name: ABprpappppa	WBbt:0004510
a type of pharyngeal cell that connects basement membrane to the apices of triangle-shaped pharyngeal lumen.	marginal cell		WBbt:0003673

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002216	klp-3	T09A5.2	Caenorhabditis elegans

6 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003