WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

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Expression Pattern :

Primary Identifier  Expr7893 Remark  Picture: Fig. 1.
Subcellular Localization  During prophase of the first mitosis in centration and rotation stage embryos, LIN-5 did not appear enriched at the cortex relative to the underlying cytoplasm. However, the anterior cortex and cytoplasm stained more intensely for LIN-5. Although both cortical and cytoplasmic LIN-5 intensities were somewhat discontinuous, most prophase embryos exhibited clear asymmetries overall: The highest levels of cortical LIN-5 staining were at the anterior from 0% to 30% egg length (33/38 cortices, n = 19 embryos; note that in some embryos the upper and lower cortex showed different patterns and thus the number of cortices, rather than embryos, was scored). In these embryos, LIN-5 staining intensities began to decrease at about 40% egg length. LIN-5 cytoplasmic intensities showed similar anterior enrichment and the traces closely matched those of cortical levels in most cases (30/38 traces). The differences between anterior and posterior intensities are statistically significant. The averaged plot also shows a bipolar appearance rather than a simple anterior to posterior gradient: the region from 50% to 70% egg length had the lowest average staining intensities.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002994 lin-5 T09A5.10 Caenorhabditis elegans

0 Life Stages