WormMine: ExpressionPattern Expr16145

• Pattern: We found that in the adult nervous system unc-42 is strongly and consistently expressed in 40 neurons located in the head of the worm that fall into 15 anatomically distinct neuron classes. At the first larval stage, expression is detected in the same set of neuron classes as observed in the adult, with the addition of very weak and inconsistent expression in AVJ and SIA that disappears by the adult stage. In the embryo, expression is first observed in a few neuroblasts before the bean stage. At the bean stage, when most neurons have terminally divided, unc-42 expression commences and reaches the full complement of unc-42(+) cells at the 1.5-fold stage. The cellular sites of expression in the embryonic nervous system appear to be the same as observed post-embryonically, a notion further supported by recent scRNA data (Packer et al., 2019). No expression is observed outside the nervous system.
• Primary Identifier: Expr16145

46 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASHL	lineage name: ABplpaappaa	WBbt:0003890
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASHR	lineage name: ABprpaappaa	WBbt:0003889
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIBDL	lineage name: ABplppaaaaa	WBbt:0004981
Ventral cord interneuron, synapses onto VA, DA, and AS motor neurons; formerly called alpha	AVAL	lineage name: ABalppaaapa	WBbt:0003870
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIBDR	lineage name: ABprppaaaaa	WBbt:0004979
Ventral cord interneuron, synapses onto VA, DA, and AS motor neurons; formerly called alpha	AVAR	lineage name: ABalaappapa	WBbt:0003869
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMDVL	lineage name: ABalppappaa	WBbt:0004970
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMDVR	lineage name: ABarappppaa	WBbt:0004969
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMDDL	lineage name: ABplpapaaaa	WBbt:0004972
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMDDR	lineage name: ABprpapaaaa	WBbt:0004971
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIBVL	lineage name: ABplpapaapp	WBbt:0004978
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIBVR	lineage name: ABprpapaapp	WBbt:0004977
Ring interneuron, anteriorly projecting process that runs sublaterally	SAAVR	lineage name: ABprpaaaaaa	WBbt:0005001
Ring interneuron, anteriorly projecting process that runs sublaterally	SAADL	lineage name: ABalppapapa	WBbt:0005007
Ring interneuron, anteriorly projecting process that runs sublaterally	SAADR	lineage name: ABarapppapa	WBbt:0005005
Ring interneuron, anteriorly projecting process that runs sublaterally	SAAVL	lineage name: ABplpaaaaaa	WBbt:0005003
Ventral cord interneuron, synapses onto VB and DB motor neurons; formerly called beta.	AVBL	lineage name: ABplpaapaap	WBbt:0003868
Ventral cord interneuron, synapses onto VB and DB motor neurons; formerly called beta.	AVBR	lineage name: ABprpaapaap	WBbt:0003867
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIAVL	lineage name: ABplpapappa	WBbt:0004985
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIAVR	lineage name: ABprpapappa	WBbt:0004983
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIADL	lineage name: ABplpapaapa	WBbt:0004989
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIADR	lineage name: ABprpapaapa	WBbt:0004987
Ring and ventral cord interneuron.	AVKL	lineage name: ABplpapapap	WBbt:0003845
Ring and ventral cord interneuron.	AVKR	lineage name: ABprpapapap	WBbt:0003844
Ring motor neuron/interneuron, many synapses	RMDL	lineage name: ABalpppapad	WBbt:0005037
Ring motor neuron/interneuron, many synapses	RMDR	lineage name: ABpraaaapad	WBbt:0005033
Ring motor neuron/interneuron, many synapses	RMDVL	lineage name: ABalppapaaa	WBbt:0005031
Amphid interneuron	AIBL	lineage name: ABplaapappa	WBbt:0003985
Amphid interneuron	AIBR	lineage name: ABpraapappa	WBbt:0003984
Ventral cord interneuron, like AVD but outputs restricted to anterior cord.	AVEL	lineage name: ABalpppaaaa	WBbt:0003864

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006778	unc-42	F58E6.10	Caenorhabditis elegans

0 Life Stages