WormMine: ExpressionPattern Expr3067

• Primary Identifier: Expr3067
• Subcellular Localization: Anti-GPA-5 antibodies were detected not only in the cilia, but also in the cell bodies and axons of the AWA neurons. Often, although faintly, staining was observed in the ADL cell bodies, but not in the ASI cells. A punctate staining pattern of the axon with anti-GPA-5 antibodies suggested that GPA-5 might be located at the synaptic sites of the AWA axons. Therefore, animals that expressed a snb-1::GFP fusion construct specifically in AWA was generated. Due to its fusion with SNB-1 synaptobrevin, green fluorescent protein (GFP) localizes to synaptic vesicles in these animals. Staining with anti-GPA-5 serum showed a punctate localization of GPA-5 close to SNB-1::GFP, suggesting that GPA-5 might function at the periactive zones of the AWA synapses.

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Amphid neuron, prob. chemosensory	ADLL	lineage name: ABalppppaad	WBbt:0003997
Amphid neuron, prob. chemosensory	ADLR	lineage name: ABpraaapaad	WBbt:0003995
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath	AWAR	lineage name: ABpraapapaa	WBbt:0003830
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath	AWAL	lineage name: ABplaapapaa	WBbt:0003831

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001667	gpa-5	F53B1.7	Caenorhabditis elegans

0 Life Stages