1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00010755 | vglu-2 | K10G9.1 | Caenorhabditis elegans |
Pattern | vglu-2::gfp is dynamically expressed in a restricted set of distinct cell types. Within the nervous system, vglu-2::gfp is exclusively expressed in a single interneuron class, AIA, where it localizes to vesicular structures in the soma, but not along the axon, suggesting that VGLU-2 may not be involved in synaptic transport of glutamate. The expression in AIA can be observed throughout alllarval and adult stages in either hermaphrodite or male animals. Outside the nervous system, VGLU-2 is expressed in collagen-producing skin cells (syncytial epidermis and in uterine tissue) where it most prominently localizes to early endosomes, and to a lesser degree apical clathrin-coated pits, TGN, and late endosomes. On early endosomes VGLU-2 colocalized most strongly with the recycling promoting factor SNX-1, a retromer component. | Primary Identifier | Expr14916 |
Subcellular Localization | vglu-2::gfp is exclusively expressed in a single interneuron class, AIA, where it localizes to vesicular structures in the soma, but not along the axon. In syncytial epidermis and in uterine tissue vglu-2::gfp most prominently localizes to early endosomes, and to a lesser degree apical clathrin-coated pits, TGN, and late endosomes. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00010755 | vglu-2 | K10G9.1 | Caenorhabditis elegans |