1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00000843 | cup-2 | F25D7.1 | Caenorhabditis elegans |
| Primary Identifier | Expr8720 | Remark | Picture: Fig. 5D. |
| Subcellular Localization | In wild-type coelomocytes, CUP-2::GFP colocalizes extensively with the smooth ER marker cytochrome b5 and the rough ER marker TRAM, indicating that at steady state, the majority of CUP-2 molecules reside in the ER. However, in addition to the ER staining, authors consistently detected CUP-2::GFP, but not the other ER markers, in peripheral organelles, suggesting that CUP-2 localizes to other compartments besides the ER. This peripheral staining was not of the Golgi complex that was visualized as discrete centralized puncta in coelomocytes. At least a portion of the peripheral CUP-2 staining was endosomal because it appeared to colocalize with RAB-5, although the elaborate nature of the ER in coelomocytes precludes an unambiguous determination. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00000843 | cup-2 | F25D7.1 | Caenorhabditis elegans |
