| Primary Identifier | Expr8618 | Remark | Picture: 3H to 3M. |
| Subcellular Localization | Immunostaining revealed that RNP-8L protein is predominantly cytoplasmic, colocalizes with the PGL-1 germ granule marker, and is abundant in the proximal pachytene region and developing oocytes. RNP-8L was detectable in males, but much less abundant than in hermaphrodites. As assessed by immunocytochemistry of male germlines, RNP-8L was limited to the mitotic region, transition zone, and distal pachytene region; it was absent from proximal pachytene cells, spermatocytes, and mature sperm. RNP-8L was similar in both hermaphrodite and male distal germlines, both with respect to its low level and its distribution in cytoplasmic granules. As assessed by western blot, RNP-8L was also low in mutant adult hermaphrodites that made only sperm and no oocytes. Abundant RNP-8L seem to be associated with oogenesis. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes. | germ line | germline | WBbt:0005784 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00020091 | rnp-8 | R119.7 | Caenorhabditis elegans |
