WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  cdc-25.2 mRNA was hardly detectable in glp-1(q224) hermaphrodites compared with N2 hermaphrodites, indicating that cdc-25.2 is preferentially expressed in the germ line. In N2 hermaphrodites, expression of cdc-25.2 mRNA was relatively low until L4 larval stage, but the expression increased significantly in young adult (YA; just after the L4 to adult molting but before egg laying has started) and adult (Ad; egg-laying gravid adult worms) stages, when oogenesis actively occurs in hermaphrodite worms. Furthermore, although cdc-25.2 mRNA was expressed in feminized fem-1(hc17lf) hermaphrodites, it was barely detectable in N2 males and in masculinized fem-3(q20gf) hermaphrodites. These results indicate that cdc-25.2 is expressed primarily in oocytes and not in sperm. However, compared with the robust expression in the N2 hermaphrodite germ line, the expression was much weaker in the feminized fem-1(lf) germ line, suggesting that the presence of sperm or fertilization positively affect the cdc-25.2 expression level. In conclusion, quantitative real-time RT-PCR showed that cdc-25.2 is predominantly expressed in oocytes of adult hermaphrodites. Primary Identifier  Expr8942
Remark  Picture: Fig 1A.

1 Anatomy Terms

Definition Name Synonym Primary Identifier
a female haploid germ cell. oocyte ovum WBbt:0006797

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000387 cdc-25.2 F16B4.8 Caenorhabditis elegans

0 Life Stages