| Primary Identifier | Expr8869 | Remark | Picture: Figure 1C. |
| Subcellular Localization | HIM-18 is first observed in mitotic nuclei at the distal tip region of the germline (premeiotic tip). However, the HIM-18 signal is abruptly reduced as nuclei enter into meiotic prophase, being barely visible in the transition zone (leptotene/zygotene) or in early to mid pachytene nuclei. HIM-18 signal is then clearly detected once again in late pachytene nuclei, persisting through the end of diakinesis. At a higher resolution, the HIM-18 signal is observed as nuclear foci (mainly around the chromosomes) in the premeiotic tip, late pachytene and diplotene/diakinesis stages. Although the HIM-18 signal is reduced from transition zone through mid-pachytene, a low level of HIM-18 foci, both on and around chromosomes, is still apparent at these stages upon longer exposure. Finally, HIM-18 is no longer observed localizing onto chromosomes after diakinesis. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes. | germ line | germline | WBbt:0005784 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00011415 | him-18 | T04A8.15 | Caenorhabditis elegans |
