1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004042 | plk-1 | C14B9.4 | Caenorhabditis elegans |
| Primary Identifier | Expr8180 | Remark | Authors found an analogous distribution using antibodies directed against GFP in transgenic animals expressing GFP-PLK-1, although the asymmetry is somewhat less pronounced in this case. Picture: Figure 1. The signals detected by these antibodies in wild-type embryos are absent from embryos depleted of PLK-1 by RNAi, demonstrating specificity. |
| Subcellular Localization | PLK-1 is distributed in a uniform manner in the cytoplasm just after meiotic exit. PLK-1 distribution becomes asymmetric shortly thereafter, with more protein present on the anterior side of the embryo. This asymmetry persists throughout the one-cell stage and until the end of the two-cell stage. Line scans quantifying pixel intensities confirm these observation. These antibodies also label centrosomes, the midbody and kinetochores. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004042 | plk-1 | C14B9.4 | Caenorhabditis elegans |
