WormMine: ExpressionPattern Expr549

• Pattern: SEL-1 appeared in all tissues except the pharynx at L1 larva through adult. SEL-1 detected in all larval stages and adult tissues, except pharynx. SEL-1 staining located in intra-cellular vesicles (SEL-1 staining present in P5.p and P7.p (and other vulval precursor cells) at the time they are deciding between alternative cell fates). SEL-1 could be detected in all larval and adult tissues, but not in the pharynx. In adults strong GFP fluorescence is seen at the apical and basal surfaces of the intestinal membranes, and in pseudocoelomic spaces. GFP is also localized in empty uterine spaces around unlaid embryos. Staining observed in a pair coelomocytes.
• Primary Identifier: Expr549
• Remark: The GFP construct rescues a sel-1 mutant.
• Subcellular Localization: intracellular vesicles.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004759	sel-1	F45D3.5	Caenorhabditis elegans

5 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024