WormMine: ExpressionPattern Expr13622

• Pattern: ACBP-4::GFP is found to be specifically localized to granular structures in the intestine. These granules are likely to be fat storage granules, as ACBP- 4::GFP expression could not be observed upon RNAi (RNA interference) knockdown of sbp-1, the C. elegans homologue of the mammalian lipogenic transcription factor SREBP-1c. Furthermore, under the light microscope, the ACBP-4::GFP-labelled granules have the smooth appearance of fat storage granules and not the more-obviously structured appearance of lysosomes. However, we cannot completely rule out the possibility that ACBP-4::GFP is also associated with lysosomes.
• Primary Identifier: Expr13622

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00018949	acbp-4	F56C9.5	Caenorhabditis elegans

0 Life Stages