WormMine: ExpressionPattern Expr16022

• Pattern: We found that TSP-14A and TSP-14B exhibit distinct expression and localization patterns. First, only TSP-14A, but not TSP-14B, is detectable in the germline and sperm cells, as well as at the tip of the anterior sensory cilia, while TSP-14B is detectable in the pharynx. Both TSP-14A and TSP-14B are found in hypodermal cellsand the developing vulva. However, the two isoforms exhibit different subcellular localization patterns. In hypodermal cells, TSP-14A is primarily localized in intracellular vesicles, while TSP-14B is mainly localized on the cell surface. In the developing vulva, TSP-14A is localized on the apical side, while TSP-14B is localized on the basolateral membrane. Similar localization patterns hold true in the pharynx.
• Primary Identifier: Expr16022
• Remark: TSP-14A isoform expression.

5 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784
Male haploid germ cell.	sperm	spermatozoa	WBbt:0006798
neuron that senses external stimuli and transduce them to signals internal to the organism.	sensory neuron		WBbt:0005759
cell that has the potential to form structural part of a vulva.	vulval precursor cell	VPC	WBbt:0007809
primary cell type that forms the hypodermis.	hypodermal cell		WBbt:0007846

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006640	tsp-14	F39C12.3	Caenorhabditis elegans

0 Life Stages