WormMine: ExpressionPattern Expr2631

• Pattern: In adult C. elegans, klp-18 mRNA expression is strongest in the female germ line. In glp-4 hermaphrodites, which have a severely under-proliferated germ line, no klp-18 transcript is detectable. In fem-2 hermaphrodites, which produce only oocytes, klp-18 transcript is present at high levels, and in fem-3 gain-of-function hermaphrodites, which produce only sperm, it is present at approximately wild-type levels. Additional northern blot analysis revealed increasing klp-18 transcript levels at progressively later stages of wild-type larval development. This increase is likely due to a growing population of germ cells.
• Primary Identifier: Expr2631

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002228	klp-18	C06G3.2	Caenorhabditis elegans

0 Life Stages