WormMine: ExpressionPattern Expr964

• Pattern: In hermaphrodites, the daz-1 mRNA was first detected in the germline of the L2 stage larva. Since germ cells enter the meiotic pathway at late L3, the onset of transcription of daz-1 appeared to precede the initiation of meiosis. The hybridization signal increased its intensity as the developmental stage progressed. During the larval stages, the daz-1 mRNA appeared more abundant at the distal region than the proximal region of the gonad. In young adult hermaphrodites, the daz-1 transcripts were detected at a very low level in the distal mitotic region of the gonad, began to accumulate in the meiotic transition zone, and reached the maximum level in the proximal pachytene region. The transcript level dropped sharply in mature oocytes. No hybridization signal was seen in the spermatheca. Compared to hermaphrodites, a much weaker signal was detected in the germline of adult males.
• Primary Identifier: Expr964

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000935	daz-1	F56D1.7	Caenorhabditis elegans

4 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038