WormMine: ExpressionPattern Expr2201

• Pattern: Expressed in germ-line cells.
• Primary Identifier: Expr2201
• Remark: Antibodies that recognize either the N or C terminus of SYP-1 do not detect SYP-1 protein on chromosomes in germ-line nuclei from syp-1(me17) mutants, further confirming the specificity of the antibody. Expression pattern in other life stages or other tissues are not reported in this article.
• Subcellular Localization: SYP-1 protein was observed along the length of synapsed chromosomes during meiotic prophase. Within the premeiotic region of the germ line, SYP-1 protein is not detectable on chromosomes. At or just prior to the beginning of the transition zone, a small number of nuclei are closely associated with one or two SYP-1 foci, while the majority of transition-zone nuclei exhibit several continuous tracks of SYP-1 staining that localize to a portion of the total DAPI-stained chromatin. In the pachytene region, nuclei exhibit highly ordered SYP-1 staining: Thick, continuous lines of SYP-1 lie at the interface between synapsed homologs along their full lengths. Finally, SYP-1 disassembles from the majority of the length of each chromosome pair by diakinesis, and is undetectable on chromosomes by the end of prophase.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006375	syp-1	F26D2.2	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The stage after an hermaphrodite animal is fully-developed and reaches maturity.		adult hermaphrodite Ce	WBls:0000057