| Pattern | SLD-2:: GFP is expressed in the distal tip and loop region of the germline. SLD-2 localization is strictly limited to the proliferative nuclei of the C. elegans germline. | Primary Identifier | Expr11591 |
| Subcellular Localization | SLD-2::GFP revealed localization to the majority of nuclei in the mitotic zone of the germline, regardless of cell cycle stage. Similarly, it was observed in early embryonic cell cycles that SLD-2 is nuclear from as soon as the nuclear membrane forms after mitosis until nuclear envelope breakdown in the next mitosis, suggesting that nuclear localization of SLD-2 is not regulated during the mitotic cell cycle. Interestingly, however, SLD-2::GFP localization ends abruptly at the meiotic transition zone, as determined by the virtual absence of GFP signal in the crescent-shaped meiotic nuclei. Although absent from the meiotic region of the germline, SLD-2::GFP reappears in developing oocyte nuclei in the loop region of the gonad and in mature oocytes. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes. | germ line | germline | WBbt:0005784 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00020466 | sld-2 | T12F5.1 | Caenorhabditis elegans |
