WormMine: ExpressionPattern Expr813

• Pattern: Only weak expression of SAD-1 was visible in wild-type animals, but in animals overexpressing SAD-1 from the endogenous promoter SAD-1 immunoreactivity was present throughout the nervous system. As with psad-1GFP, expression was first seen in the late embryo. Observed no consistent anti-SAD-1 staining in sad-1(ky289) null animals,suggesting that the antibodies are specific for SAD-1 protein. The onset of sad-1 expression in the late embryo is consistent with a role for SAD-1 in synaptogenesis, as this is the time when many synapses are first made.
• Primary Identifier: Expr813
• Subcellular Localization: Fluorescence appeared as a combination of punctate and diffuse staining within the axon.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Complement of nervous tissue (neurones, nerves, receptors and support cells) serving to detect, relay and coordinate information about an animal`s internal and external environments and to initiate and integrate its effector responses and activities.	nervous system		WBbt:0005735

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004719	sad-1	F15A2.6	Caenorhabditis elegans

6 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003