1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00008719 | ttr-52 | F11F1.7 | Caenorhabditis elegans |
Primary Identifier | Expr9060 | Remark | Expression of a TTR-52mCherry (monomeric Cherry) fusion under the control of the heat-shock promoters or the ttr-52 promoter resulted in the same staining pattern. The staining of TTR-52mCherry or TTR-52GFP on the surface of dying cells was abolished by a loss-of-function mutation in the ced-3 gene (n717), which blocks almost all apoptosis in C. elegans 30, confirming that the cells labelled by TTR-52 were apoptotic cells. Picture: Fig 2c, 3a, 3b, Fig. S2. |
Subcellular Localization | On heat-shock treatment, TTR-52GFP was detected almost exclusively on the surface of apoptotic cells, showing a bright ring-like staining. In some embryos, weak GFP staining was also observed on the surface of cells adjacent to the dying cells. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00008719 | ttr-52 | F11F1.7 | Caenorhabditis elegans |