WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr9060 Remark  Expression of a TTR-52mCherry (monomeric Cherry) fusion under the control of the heat-shock promoters or the ttr-52 promoter resulted in the same staining pattern. The staining of TTR-52mCherry or TTR-52GFP on the surface of dying cells was abolished by a loss-of-function mutation in the ced-3 gene (n717), which blocks almost all apoptosis in C. elegans 30, confirming that the cells labelled by TTR-52 were apoptotic cells. Picture: Fig 2c, 3a, 3b, Fig. S2.
Subcellular Localization  On heat-shock treatment, TTR-52GFP was detected almost exclusively on the surface of apoptotic cells, showing a bright ring-like staining. In some embryos, weak GFP staining was also observed on the surface of cells adjacent to the dying cells.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00008719 ttr-52 F11F1.7 Caenorhabditis elegans

0 Life Stages