1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00000192 | arl-8 | Y57G11C.13 | Caenorhabditis elegans |
Primary Identifier | Expr9048 | Remark | Picture: Figure 1D, 1E, 1F. |
Subcellular Localization | Double labeling of ARL-8::mCherry with endocytic compartment GFP-markers showed that ARL-8::mCherry did not overlap with 2xFYVE::GFP (early endosomes) or RME-8::GFP (early/late endosomes). In contrast, most ARL-8::mCherry colocalized well with GFP::RAB-7 (late endosomes/lysosomes) and LMP-1::GFP (lysosomes). More precisely, ARL-8::mCherry showed virtually complete overlap with LMP-1::GFP, whereas there were some GFP::RAB-7positive compartments lacking ARL-8::mCherry. These results indicate that C. elegans Arl8 localizes primarily to lysosomes. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00000192 | arl-8 | Y57G11C.13 | Caenorhabditis elegans |