1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00011580 | ddx-19 | T07D4.4 | Caenorhabditis elegans |
Primary Identifier | Expr9012 | Remark | Picture: Fig 3A, 3F, 3G, 4A, 4B. |
Subcellular Localization | Anti-DDX-19 showed low levels of staining at the nuclear rim and in the cytoplasm of somatic cells but much stronger staining on germ nuclei; staining diminished or disappeared on late oogonial nuclei that cease transcription. At high magnification, DDX-19 appeared concentrated in patches on both adult and larval germ nuclei. Co-staining with anti-NPP-9 and anti-PGL-1 showed that the vast majority of DDX-19 was localized at Pg-NPCs(nuclear pore complexes): in the data set of 100 large patches of NPP-9, 94% of the P granule-positive patches colocalized with a patch of DDX-19. The profile of each DDX-19 patch typically was smaller than the associated patch of NPP-9 but similar to that of PGL-1. In cross-sections of nuclei, DDX-19 appeared concentrated between the zones of PGL-1 and NPP-9, forming a tripartite sandwich; remarkably, P granules initially maintained a similar, tripartite appearance after detaching from oogonia nuclei. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00011580 | ddx-19 | T07D4.4 | Caenorhabditis elegans |