WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  Expression was observed in descendants of both ABalap and MSap. Reproducible beta-galactosidase was first observed in all four ABala granddaughters at the 55-cell (late 32 AB-cell) stage in embryos expressing the lag-2::lacZ reporter. Beta-galactosidase was not detected in any other cells of the AB lineage at this stage in development. Expression of beta-galactosidase was also observed in MSap descendants; at the 87-cell (64 AB-cell) stage, beta-galactosidase was observed in MSapa and MSapp, the daughters of MSap. Beta-galactosidase expression in both the ABala and MSap lineages persists for at least two rounds of cell division. This observation may reflect actual expression of the lag-2 gene, rather than a perdurance of beta-galactosidase protein, because an engineered beta-galactosidase with a short half-life was used in the construction of the translational fusion. No lag-2 expression were observed in ABalap and MSap, the proposed signaling cells of the ABplaa and ABplpa inductions, respectively. Instead, lag-2 expression was first detected at later stages, in descendants of these cells. Primary Identifier  Expr1611
Remark  Reporter gene fusion type not specified.
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12 Anatomy Terms

Definition Name Synonym Primary Identifier
embryonic cell ABala   WBbt:0006707
embryonic cell ABalaa   WBbt:0006039
embryonic cell MSapa   WBbt:0005898
embryonic cell ABalapp   WBbt:0005946
embryonic cell ABalaap   WBbt:0005907
embryonic cell MSapp   WBbt:0006036
embryonic cell MSappp   WBbt:0006125
embryonic cell MSapaa   WBbt:0006236
embryonic cell ABalaaa   WBbt:0006216
embryonic cell MSapap   WBbt:0006475
embryonic cell ABalapa   WBbt:0006652
embryonic cell MSappa   WBbt:0006717

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002246 lag-2 Y73C8B.4 Caenorhabditis elegans

1 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The C. elegans life stage spanning 100-290min after first cleavage at 20 Centigrade. Proliferate from 28 cells to 421 cells. Referring to the whole period of gastrulation. gastrulating embryo Ce WBls:0000010