WormMine: ExpressionPattern Expr4000

• Pattern: Embryonic med transcripts accumulate in the EMS nucleus at the 4-cell stage, become cytoplasmic in MS and E, and are undetectable thereafter. Signal was also observed in the gonads of all adults, with 68% (174/257) showing very strong staining, while very little or no gonadal signal was observed using sense probes. Authors did not detect significant levels of med transcripts in very early embryos or late oocytes.
• Primary Identifier: Expr4000
• Remark: In the related nematode, C. briggsae, in situ hybridization with a Cb-med-1 probe reveals gonadal as well as embryonic signal in EMS.
• Subcellular Localization: Embryonic med transcripts accumulate in the EMS nucleus at the 4-cell stage, become cytoplasmic in MS and E.

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
organ producing either sperm or ova.	gonad		WBbt:0005175
Embryonic founder cell	MS	lineage name: P0.paa	WBbt:0004458
Embryonic founder cell	E	lineage name: P0.pap	WBbt:0004804
embryonic cell	EMS		WBbt:0006876

2 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003180	med-1	T24D3.1	Caenorhabditis elegans
WBGene00003181	med-2	K04C2.6	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The C. elegans life stage spanning 0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage until the start of gastrulation.		blastula embryo Ce	WBls:0000005