WormMine: ExpressionPattern Expr966

• Pattern: PAR-4 protein is apparent in the gonads of adult hermaphrodites and in oocytes. 1-cell embryos show cytoplasmic staining and faint cortical staining. No asymmetry in the distribution of PAR-4 protein in the cytoplasm or at the cell periphery was observed. Cortical staining is stronger at the time of first cleavage, with prominent PAR-4 staining of the cleavage furrow. The cortical staining remains at high levels at the 2-cell and 4-cell stages and continues to be present in all blastomeres through early development. Staining of late stage embryos is reduced, but the germline precursor cells, Z2 and Z3, show somewhat stronger cortical staining than other cells.
• Primary Identifier: Expr966
• Subcellular Localization: At the actin-rich boundaries in the gonads of adult hermaphrodites between nuclei in the syncitial region. In oocytes, the protein is present in the cytoplasm, is excluded by nuclei and is faintly present at the cell periphery.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
organ producing either sperm or ova.	gonad		WBbt:0005175

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003919	par-4	Y59A8B.14	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	The stage after an hermaphrodite animal is fully-developed and reaches maturity.		adult hermaphrodite Ce	WBls:0000057