WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  Expressed in gonad. Primary Identifier  Expr2647
Subcellular Localization  Immunostaining of RAD-51 showed that it forms distinct round or slightly elongated dots within nuclei of the gonad. RAD-51 spots was only occasionally observed in mitotic cells. No RAD-51 staining was observed in rad-51(lg08701) worms or when a pre-immune serum was used. However, RAD-51 foci were readily induced in mitotic cells upon irradiation in a dose- and time-dependent manner. The number of RAD-51 spots was very heterogeneous between cells at comparable stages within one and the same gonad. In a small fraction of nuclei in the mitotic zone 1 or 2 spots occurred. In meiotic cells RAD-51 foci appeared in nuclei of the transition zone of the gonad, which corresponds to the leptotene to zygotene stage. Many of the RAD-51 spots were bar-shaped. In nuclei immediately adjacent to the transition zone (which correspond to late zygotene/early pachytene) up to nine RAD-51 spots were present, whereas by late pachytene they were gone.

1 Anatomy Terms

Definition Name Synonym Primary Identifier
organ producing either sperm or ova. gonad   WBbt:0005175

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004297 rad-51 Y43C5A.6 Caenorhabditis elegans

0 Life Stages