WormMine: ExpressionPattern Expr1252

• Pattern: The DNA topoisomerase I mRNA level gradually increase through meiotic progression starting from mitotic cells at the distal tip end of a gonad. The mRNA was also localized in embryos from the very beginning of embryogenesis, which seems very likely to be of maternal origin, and the level of mRNA was kept high during the earlier half of embryogenesis. In the later half period, the mRNA began to disappear rapidly and was almost completely gone at the 3-fold stage right before hatching.
• Primary Identifier: Expr1252

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
organ producing either sperm or ova.	gonad		WBbt:0005175

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006595	top-1	M01E5.5	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	The stage after an hermaphrodite animal is fully-developed and reaches maturity.		adult hermaphrodite Ce	WBls:0000057