WormMine: AnatomyTerm WBbt:0007813

• Definition: any of six ventral uterine intermediate precursor cells that are adjacent to the anchor cell and whose progeny are fated to become uv1 and utse cells.
• Name: uterine pi cell
• Primary Identifier: WBbt:0007813

2 Children

Definition	Name	Synonym	Primary Identifier
uterine pi cell that follows the 5R configuration of development.	uterine pi cell (5R)		WBbt:0008309
uterine pi cell that follows the 5L configuration of development.	uterine pi cell (5L)		WBbt:0008308

0 Expression Clusters

6 Expression Patterns

• Primary Identifier: Expr9638
• Pattern: nhr-67::gfp was expressed at all postembryonic stages in neurons of the head. nhr-67::gfp expression was not observed in uterine or vulval precursor in embryos or L1 larvae. In the L2 stage, nhr-67::gfp expression was observed in the 4 pre-VU precursor cells (Z1.ppa, Z1.ppp, Z4.aaa, Z4.aap) that become the AC and the three VU cells that give rise to the ventral uterus. Expression of nhr-67::gfp in the 4 pre-VU precursor cells appeared at or shortly after their birth. In the mid- to late-L2 stage, expression of nhr-67::gfp in the three VU cells decreased, while remaining at high levels (or possibly increasing) in the AC. During the L3 and early L4 stages, consistent and continual bright nhr-67::gfp expression was observed in the AC and more variable weak levels of expression were found in the six adjacent pi cells. nhr-67::gfp expression was very rarely detected in all 12 pi cells after their dorsal-ventral division. From early L4 through adulthood, weak expression of nhr-67::gfp was observed in all 8 UTSE cells or syncytium, suggesting that expression is turned off in all pi cells after their division and then re-expressed later in UTSE. Expression of nhr-67::gfp was observed in the UTSE before AC fusion. Bright expression of nhr-67::gfp in the AC nucleus was not observed after mid-L4, indicating that it is reduced after fusion of the AC with the UTSE syncytium.

• Primary Identifier: Expr10618
• Pattern: A functional MADD-2: GFP reporter was strongly expressed in the AC and more weakly in the adjacent uterine cells around the time of invasion (Pn.px to Pn.pxx stages). The MADD-2: GFP signal was slightly polarized toward the basal side of the AC, where the invasive membrane forms.

• Primary Identifier: Expr11184
• Pattern: The authors observed that a fos-1a translational fusion is expressed throughout the VU intermediate prescursor cells, including pi cells.

• Primary Identifier: Expr11185
• Pattern: plastFOS-1c::YFP showed expression primarily in the early dorsal and ventral uterus during L3 and L4 stages. Importantly, expression was observed in all VU intermediate precursors including pi cells. Furthermore, the authors confirmed that plastFOS-1c::YFP co-localized with cells expressing an egl-13 pi marker from the late L3 induction stage through generation of pi descendants.

• Primary Identifier: Expr11013
• Pattern: In wild-type animals, the six uterine pi cell express cog-2::gfp at the early- to mid-L4 stage.

• Primary Identifier: Expr11398
• Remark: Feature : lin-11 enhancer
• Pattern: Examination of GFP fluorescence in transgenic animals revealed that the mpA-3 region is capable of activating lin-11p::GFP expression in uterine pi lineage cells.

0 Life Stages

1 Parents

Definition	Name	Synonym	Primary Identifier
precursor cell destined to divide some time after hatching.	blast cell		WBbt:0006783