1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00001017 | dnc-1 | ZK593.5 | Caenorhabditis elegans |
Primary Identifier | Expr9603 | Remark | Picture: Fig. 1A-C; supplementary material Movie 1, supplementary material Fig. S1A. |
Subcellular Localization | This dynamic dynactin accumulation was confirmed by immunofluorescence staining with anti-DNC-1 antibody. When examined at the four-cell stage during P2 and EMS spindle rotation, DNC-1::GFP was enriched at the cell border between P2 and EMS prior to and during EMS and P2 spindle rotation. The accumulation first appeared at 8.88+/-0.63 minutes after the first appearance of the cleavage furrow in P1 (n=5, measured with DNC-2::GFP embryos) and remained there for 6.8+/-0.7 minutes (n=5). Dynactin-labeled EMS and P2 centrosomes rotated and moved such that one centrosome from each spindle became closely apposed to the accumulation site.Authors also observed instances of dynactin-labeled putative microtubule (MT) plus-ends emanating from one centrosome and terminating at this accumulation site. The accumulation was then observed to disappear about 4.77+/-0.78 minutes (n=5) before EMS cleaved. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00001017 | dnc-1 | ZK593.5 | Caenorhabditis elegans |