WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr3188 Subcellular Localization  Antibodies were raised against C. elegans SAS-6 that recognize a single band of the predicted size in wild-type embryonic extracts, which is severely diminished in sas-6(RNAi) embryonic extracts. These antibodies preferentially label a dot in the centre of the centrosome in early embryos, as well as in the cytoplasm to a lesser extent. The signal is vastly diminished in sas-6(RNAi) embryos, indicating specificity. Furthermore, SAS-6 colocalizes with GFP::SAS-4 and GFP::SAS-5 in sperm cells. The distribution of SAS-6 appears to be more restricted than that of either fusion protein, indicating that SAS-6 may be present in only part of the centrioles, although immunoelectron microscopy will be needed to ascertain this point.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00012888 sas-6 Y45F10D.9 Caenorhabditis elegans

0 Life Stages