WormMine: ExpressionPattern Expr3090

• Pattern: An hlh-2::lacZ transcriptional reporter appears to be expressed in a similar pattern to HLH-2 protein during the L1 stage. HLH-2 does not accumulate detectably in any cell of the gonad until Z1 and Z4 have undergone two rounds of division, near the end of the L1 stage. HLH-2 was consistently observed in the DTCs (Z1.aa and Z4.pp) and in the presumptive AC and mature AC. HLH-2 was also weakly and inconsistently present in Z1.pp and Z4.aa (the parents of Z1.ppp and Z4.aaa), as well as their sisters, Z1.pa and Z4.ap.
• Primary Identifier: Expr3090
• Subcellular Localization: While HLH-2 accumulation in the DTCs is nuclear, as expected for a transcription factor, HLH-2 is detectable in the cytoplasm as well as the nucleus of other gonadal cells.

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	anterior distal tip cell	gon herm dtc A	WBbt:0004520
Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	posterior distal tip cell	gon herm dtc P	WBbt:0004506
post-embryonic cell of pedigree Z4.ap	Z4.ap		WBbt:0007756
post-embryonic cell of pedigree Z1.pa	Z1.pa		WBbt:0007594
post-embryonic cell of pedigree Z1.pp	Z1.pp		WBbt:0007627
post-embryonic cell of pedigree Z4.aa	Z4.aa		WBbt:0007687

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001949	hlh-2	M05B5.5	Caenorhabditis elegans

0 Life Stages