WormMine: AnatomyTerm WBbt:0004534

• Definition: Excretory socket cell, links duct to hypodermis
• Name: excretory socket cell
• Primary Identifier: WBbt:0004534
• Synonym: exc socket

2 Children

Definition	Name	Synonym	Primary Identifier
The outlet of the excretory sinus to the exterior environment through the cuticle, on the ventral side of the head, just behind the nerve ring.	excretory pore	pore	WBbt:0005778
nucleus of pedigree G2.p	G2.p nucleus		WBbt:0002008

0 Expression Clusters

7 Expression Patterns

• Primary Identifier: Expr11306
• Pattern: Strong expression in young larvae, progressively weaker in older larvae and adults, hypodermis (incl. seam cells), rectal epithelium, pharyngeal muscle (usually very weak), gut, arcade cells, excretory duct and pore cells, OLQs(?)

• Primary Identifier: Expr12890
• Pattern: In CD1002, transgenic for pMPFG1 (Pfmo-4::GFP) that contains ~4 kb of fmo-4 5' flanking sequence, GFP was expressed diffusely throughout the syncytial hypodermis, including head and tail hyp cells, but was absent from seam cells. Prominent GFP expression was also observed in cells flanking the vulval slit and, most noticeably, in the duct and pore cells just anterior to the posterior bulb of the pharynx. Essentially the same GFP expression was observed in both CD1018, transgenic for the fosmid-based reporter fMW002 (Pfmo-4::fmo-4:: GFP), and BC14787 (rCesF53F4.5::GFP) (McKay et al., 2003) in which the PCR-generated Pfmo-4::GFP transgene drives gfp expression with ~2.5 kb of upstream sequence. GFP expression in the duct and pore cell bodies was clearly visible under higher magnification in all three strains and was also observed in CD1002 and BC14787 outlining the distal section of the excretory duct up to the location of the excretory pore. GFP expression was not observed in the body or canals of the adjacent excretory cell.

• Primary Identifier: Expr13008
• Pattern: A let-653 promoter::GFP transcriptional reporter was expressed in external (cuticle-producing) epithelial cells, including the epidermis, vulva, rectum and excretory duct and pore, but was mostly excluded from internal epithelia such as the pharynx, intestine and excretory canal cell. Occasionally, let-653pro::GFP expression was observed in the canal cells of embryos, but this expression disappeared in later stages LET-653 fusion proteins were never observed in the canal cell.

• Primary Identifier: Expr13977
• Pattern: In hermaphrodites, expression of Pddo-3::mCherry was observed in the excretory pore cell from the late embryonic stage, in head tip cells from larval stage L3, in vulval cells from L4, and in hypodermal cells and proximal gonadal sheath cells from the adult stage.

• Primary Identifier: Expr13978
• Pattern: In males, Pddo-3::mCherry was expressed in the excretory pore cell, head tip cells, and hypodermal cells, in a pattern similar to that observed in hermaphrodites. Moreover, this reporter protein was expressed in seminal vesicle cells from L4 and in tail cells and spicule cells from the adult stage.

• Primary Identifier: Expr10531
• Pattern: atf-2::gfp expresses in the excretory duct cell, as well as other cells in the animal including the excretory pore cell and cells of the egg-laying and digestive systems (data not shown). atf-2::gfp expression initiates in the embryo and persists into larval and adult stages.

• Primary Identifier: Expr13009
• Subcellular Localization: In the vulva and likely in the excretory duct and pore tubes, LET-653 localizes transiently to two distinct pre-cuticular apical extracellular matrix compartments.

0 Life Stages

3 Parents

Definition	Name	Synonym	Primary Identifier
	excretory system		WBbt:0005736
Postembryonic blast cell, excretory socket in L1, G2.p becomes socket later	G2	lineage name: ABplapaapa	WBbt:0004779
an epithelial cell that serves either to bridge two neighboring epithelial tissues or to form an opening in the epithelium.	interfacial epithelial cell	interfacial cell	WBbt:0005754