WormMine: AnatomyTerm WBbt:0008598

• Definition: One of a pair of lateral neuroblasts that migrate separately within the body cavity during larval stages to produce a variety of cell types.
• Name: Q cell
• Primary Identifier: WBbt:0008598

2 Children

Definition	Name	Synonym	Primary Identifier
Postembryonic neuroblast, migrates posteriorly.	QL	lineage name: ABplapapaaa	WBbt:0004056
Postembryonic neuroblast, migrates anteriorly.	QR	lineage name: ABprapapaaa	WBbt:0004054

0 Expression Clusters

8 Expression Patterns

• Primary Identifier: Expr13648
• Pattern: We expressed GFP-tagged ABL-1 in Q cells and found that ABL-1::GFP was 2.2-fold enriched at the leading edge compared with the cytosolic fluorescence. AQR expresses GFP-tagged ABL-1.

• Primary Identifier: Expr13282
• Pattern: The knockin strain shows significant Msx/vab-15 expression in embryonic AB.p(lr)apapaa, which is the mother cell of Q and V5 neuroblasts. After the division of this mother cell, Msx/vab-15 expression turns off in V5 neuroblasts but is maintained in Q cells until they divide. P-neuroblast expression of Msx/vab-15 starts before hatching, is maintained while P nuclei migrate into the ventral midline in early L1-stage larvae, and shuts down after P neuroblasts divide.

• Primary Identifier: Expr13649
• Pattern: SEM-5 localized at the leading edge of Q cells.

• Primary Identifier: Expr13650
• Pattern: ARX-2::GFP occupied 89% of the periphery of the leading edge.

• Primary Identifier: Expr13651
• Pattern: WASP was detected at the leading edge, and under a 1503 objective the GFP::WSP-1 signal was resolved to separate puncta, which was not previously reported in migrating cells of live animals but may represent its real behavior at the endogenous expression level. GFP::WSP-1, GFP::WVE-1, and ARX-2::GFP occupied 36%, 53%, and 89%, respectively, of the periphery of the leading edge.

• Primary Identifier: Expr13652
• Pattern: GFP::WVE-1 and ARX-2::GFP accumulate at the leading edge: some of their signal is resolved as clusters, whereas other dense signal forms restricted segments. GFP::WSP-1, GFP::WVE-1, and ARX-2::GFP occupied 36%, 53%, and 89%, respectively, of the periphery of the leading edge.

• Primary Identifier: Expr13399
• Pattern: In support of a role of ARX-2 in Q cell corpse clearance, ARX-2::GFP was recruited onto Q cell corpses at 37 ± 9 min (mean ± SD; n = 20) after Q cell birth, and the ARX-2::GFP rings lasted for 19 ± 9 min (n = 20). The corpse was completely degraded 34 ± 18 min (n = 20) after the disappearance of ARX-2::GFP, which suggests that ARX-2 may function during the engulfment of Q cell corpses but may not be involved in the final degradation inside the phagosome.

• Primary Identifier: Expr13400
• Pattern: A triple fluorescence animal that expresses ARX-2::TagRFP knock-in, GFP::WSP-1 knock-in, and the Q cell marker Plin-32::TagBFP shows that the majority of ARX-2:: TagRFP was recruited on the Q cell corpse at approximately the same time as GFP::WSP-1 and that the ARX-2::TagRFP fluorescence was largely co-localized with GFP::WSP-1 (n = 10).

0 Life Stages

1 Parents

Definition	Name	Synonym	Primary Identifier
precursor cell destined to divide some time after hatching.	blast cell		WBbt:0006783