| Pattern | Immunohistochemical analysis of the transgene revealed that SAM-4 is localized primarily to the nerve ring region of the head, indicating that sam-4 is broadly expressed in the nervous system. | Primary Identifier | Expr12013 |
| Subcellular Localization | SAM-4 preferentially accumulates in the synaptic varicosities of PLMs and small quantities of SAM-4 accumulate as puncta in the neurites. Further examination demonstrated that these SAM-4 particles colocalize well with the RAB-3 labeled SV particles. By cell fractionation it was observed that, like the SV protein synaptobrevin SNB-1, SAM-4 was present in the SV membrane containing pellet but was absent from the cytosolic fraction, indicating that SAM-4 is likely associated with SVs. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes. | nerve ring | circumpharyngeal nerve ring | WBbt:0006749 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00019126 | sam-4 | F59E12.11 | Caenorhabditis elegans |
