1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00003404 | mpz-1 | C52A11.4 | Caenorhabditis elegans |
Primary Identifier | Expr3961 | Remark | To confirm the synaptic localization of these neuronal puncta, MPZ-1/CFP and synaptobrevin/YFP (vesicle associated membrane protein, VAMP), a presynaptic marker, were coexpressed under the control of mpz-1 promoter 2 to direct neuronal expression. As predicted, YFP::CFP colocalization was observed in most puncta; however, a few exhibited YFP fluorescence alone. |
Subcellular Localization | The expression of full length MPZ-1 from the individual mpz-1 promoters exhibited discrete subcellular localizations. Fluorescence in body wall muscle exhibited faint striations marked with puncta. In vulval muscle GFP fluorescence was concentrated at cell membranes around the vulval opening. This vulval localization was quite similar to that observed for SER-1::GFP. In neurons, MPZ-1::GFP fluorescence was concentrated in cell bodies and was punctate in the sublateral processes and ventral cord, suggesting a synaptic localization. At lower expression levels discrete puncta were also observed in neuron cell bodies. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00003404 | mpz-1 | C52A11.4 | Caenorhabditis elegans |