1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00019002 | syp-6 | F57B10.4 | Caenorhabditis elegans |
| Primary Identifier | Expr15018 | Subcellular Localization | Y54E10A.12 and F57B10.4 were initially colocalized within SC-like protein aggregates in the nucleoplasm known as polycomplexes. Both proteins then loaded onto chromosomes as chromosome pairs and were found along the entire length of chromosomes in pachytene, which perfectly mirrors the localization of SYP-2. These data suggest that Y54E10A.12 and F57B10.4 are novel components of the SC; thus, hereafter, we refer to the genes that encode them as syp-5 (Y54E10A.12) and syp-6 (F57B10.4), reflecting their physical order on chromosome I. We note that the level of SYP-6 decreased at the end of pachytene and was no longer detected in diplotene. In contrast, SYP-5 was detected on the 'short arm' of the SC in diplotene relative to the crossover site, which defines the site of cohesion loss in meiosis I (Kaitna et al., 2002; Rogers et al., 2002), and persisted until the SC fully disassembled in diakinesis, similar to the other SYP proteins in C. elegans. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00019002 | syp-6 | F57B10.4 | Caenorhabditis elegans |
