1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004874 | smc-4 | F35G12.8 | Caenorhabditis elegans |
| Primary Identifier | Expr1858 | Remark | No detailed description on cellular expression patterns. |
| Subcellular Localization | SMC-4 antibody staining showed that SMC-4 localized to mitotic chromosomes in a dynamic pattern with two striking features. First, SMC-4 localized to chromosomes only at times of the cell cycle when they were condensed. Little or no SMC-4 was observed on decondensed chromosomes during interphase. SMC-4 localized to chromosomes at prometaphase, when the six C. elegans chromosomes, but not their sister chromatids, become visibly distinct. SMC-4 persisted through metaphase and anaphase, then disappeared again as chromosomes decondensed and entered telophase. Second, SMC-4 associated only with certain regions of the chromosomes. SMC-4 appeared in a faint speckled pattern during prophase, then appeared in two stripes outlining each chromosome during prometaphase. When chromosomes were aligned at metaphase, SMC-4 localized to distinct foci on the poleward sides of the metaphase plate. The foci appear as paired spots of staining in cross-section and may represent the poleward sides of paired sister chromatids. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004874 | smc-4 | F35G12.8 | Caenorhabditis elegans |
