1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004737 | scc-1 | F10G7.4 | Caenorhabditis elegans |
| Primary Identifier | Expr11962 | Subcellular Localization | The C. elegans mitotic kleisin SCC-1, previously thought to function only during mitosis, contributes to cohesion in pachytene nuclei. SCC-1 associates with axial structures of transition zone and pachytene nuclei of wild-type animals. SCC-1 staining was detected between homologs, suggesting that SCC-1 cohesin associates with the meiotic chromosomal axis, similar to REC-8 and COH-3/4 cohesins. Diffuse nuclear staining obscured any chromosomal signal in diplotene/diakinesis nuclei; however, SCC-1 was undetectable on chromosomes following nuclear envelope breakdown, when the nucleoplasmic signal dissipated. Thus, any role played by SCC-1 in meiotic SCC of wild-type animals or kleisin triple mutants is likely to occur during pachytene, but not prometaphase I. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004737 | scc-1 | F10G7.4 | Caenorhabditis elegans |
