1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004101 | hgrs-1 | C07G1.5 | Caenorhabditis elegans |
| Primary Identifier | Expr3953 | Remark | Picture: Figures S7. |
| Subcellular Localization | In cells that express Pced-1 hgrs-1::gfp or Pced-1 hgrs-1::mrfp1, the HGRS-1 fusion proteins were observed in the cytoplasm as puncta and patches. To determine if the puncta and patches represent endosomal compartments, authors first examined whether HGRS-1::GFP co-localized with fluorescent dye FM 4-64, which is endocytosed into cells and labels endocytic compartments. FM 4-64 introduced into adult C. elegans hermaphrodites by soaking displays a punctate localization pattern in the cytoplasm typical for endosomes and lysosomes. Authors incubated L4-stage worms expressing Pced-1 hgrs-1::gfp in a buffer containing FM 4-64 (160 uM) for 1 hr and observed co-localization of HGRS-1::GFP and FM 4-64 on a large number of puncta, indicating that HGRS-1 is associated with endocytic compartments. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004101 | hgrs-1 | C07G1.5 | Caenorhabditis elegans |
