WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Life Stage :

Definition  Any Brugia developmental stage, including embryo, larva and adult stage. Primary Identifier  WBls:0000091
Public Name  Brugia life stage
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0 Anatomy Terms

1 Contained In

Remark Definition Other Name Public Name Primary Identifier
  The nematode life-cycle stage that occurs entirely or partially within a host or vector organism. parasitic nematode stage WBls:0000059

19 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P1
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P13
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P7
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P3
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P8
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P10
  Time-course transcript abundance profiles. C1 - C3, B. malayi transcripts displaying periodic patterns with respect to molting events during development in Ae. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_C3
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P4
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P6
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P11
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P5
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P16
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P9
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P12
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P14
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P15
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P2
  Time-course transcript abundance profiles. C1 - C3, B. malayi transcripts displaying periodic patterns with respect to molting events during development in Ae. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_C1
  Time-course transcript abundance profiles. C1 - C3, B. malayi transcripts displaying periodic patterns with respect to molting events during development in Ae. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_C2

2 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
    Expr11518 Bma-pdi-2 is abundantly expressed in all stages examined.  
    Expr11517 Bma-phy-1 is abundantly expressed in all stages examined.  

0 Followed By

0 Preceded By

7 Sub Stages

Remark Definition Other Name Public Name Primary Identifier
  The whole period of embryogenesis in a roundworm of the genus Brugia, from the formation of an egg until hatching. Brugia embryo WBls:0000092
  The animals have a significant "prepatent" period in the host, where they have moulted to adults but not yet started producing eggs or sperm; this stage is usually-should be conditioned by days post infection, with day 26 to approximately day 60 being the "young adult" in most systems - but note that the speed of development is different in different host genotypes. Brugia young adult WBls:0000100
  A developemental life stage in a roundworm of the genus Brugia that occurs from egg hatching until death. Brugia postembryonic stage WBls:0000093
  Derived from the host after reintroduction by vector feeding or manual inoculation; these piL3 samples are often-should be conditioned by age (hours or days post-infection). Brugia post-infection L3 WBls:0000099
  From Lima bean to hatching. Brugia late embryo WBls:0000096
  Proliferates from 100 cells to Lima bean stage. Brugia middle embryo WBls:0000095
  Proliferates from 1 to 100 cells. As the Brugia female reproductive tract is long (>10 cm), it is possible to dissect it and select early embryos just by isolating early parts of the post-spermatheca uterus. Brugia early embryo WBls:0000094