WormMine: ExpressionPattern Expr14834

• Primary Identifier: Expr14834
• Subcellular Localization: As previously reported (HARPER et al. 2011; LABELLA et al. 2011), PLK-2 became concentrated in bright foci and patches at the nuclear envelope (NE) upon entry into meiotic prophase; these NE-associated foci and patches illustrate the localization of PLK-2 at chromosome-NE attachment sites, where PLK-2 promotes PC-led chromosome movements that are important for homolog pairing and synapsis. NE localization of PLK-2 was lost by the end of early pachytene, and PLK-2 subsequently became localized to the SCs. In addition to these previously reported localization patterns, however, we also detected a strong nucleoplasmic localization of PLK-2 in premeiotic germ cell nuclei As previously reported (HARPER et al. 2011; LABELLA et al. 2011), PLK-2 became concentrated in bright foci and patches at the nuclear envelope (NE) upon entry into meiotic prophase; these NE-associated foci and patches illustrate the localization of PLK-2 at chromosome-NE attachment sites, where PLK-2 promotes PC-led chromosome movements that are important for homolog pairing and synapsis. NE localization of PLK-2 was lost by the end of early pachytene, and PLK-2 subsequently became localized to the SCs. In addition to these previously reported localization patterns, however, we also detected a strong nucleoplasmic localization of PLK-2 in premeiotic germ cell nuclei.

0 Anatomy Terms

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004043	plk-2	Y71F9B.7	Caenorhabditis elegans

0 Life Stages