1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00006540 | tbg-1 | F58A4.8 | Caenorhabditis elegans |
| Primary Identifier | Expr1645 | Remark | No detailed description for cellular expression pattern. Probably expressed everywhere. --wjc. |
| Subcellular Localization | After affinity purification, the antibodies stained centrosomes brightly. In newly fertilized embryos, gamma-tubulin antibodies did not stain the maternal meiotic spindle, which is barrel shaped and lacks centrioles and asters. Centrosome staining was seen first as 2 small dots near the sperm pronucleus at the posterior pole. This is consistent with recruitment of maternal gamma-tubulin by sperm-supplied centrioles. The small dots of gamma-tubulin grew into bright spheres as the male and female pronuclei migrated to meet in the posterior hemisphere of the embryo. In later-stage embryos, gamma-tubulin antibodies stained tiny centrosomes in interphase cells and larger centrosomes in mitotic cells. Anti-gamma-tubulin immunofluorescence signal from centrosomes was reduced below detection in embryos from hermaphrodites injected with dsRNA made from the gamma-tubulin gene, confirming the specificity of the antibodies. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00006540 | tbg-1 | F58A4.8 | Caenorhabditis elegans |
